Sorry, you need to enable JavaScript to visit this website.
About the Foundation
Home : Magazine : Trick or truth? : Keto diet
The keto diet
Jelena Ristic

The craze for the ketogenic diet has now gone global. However, its credo “sugar is dead, long live fat” seems partly counterintuitive.

The ketogenic diet, aka the keto or LCHF (low-carb, high-fat) diet, is all the rage, overtaking the Paleo diet and veganism in Google searches. Resembling a western cultural movement, adopted by a host of celebrities, it even has its own festival in Quebec.


Eat fat to lose weight?

It would appear that eating fat is a good way to lose weight. Is that really possible? Yes, but only if we cut out another foodstuff to which we are particularly partial: sugar. That means sugar in all forms, whether cereals, starchy food, or fruit, not to mention desserts and sugary drinks, which in any case should be consumed in moderation. The principle behind LCHF diets is simple: Unlike proteins and fats, we do not actually need carbohydrates in our diet, as they are not essential nutrients.1

How does it work?

LCHF diets imitate fasting, without us actually having to stop eating. They lead to weight loss by ‘burning’ our stored fat. Without any sugar intake, the body draws on its store of glycogen.2 Once this is depleted, the liver metabolises fat to generate ketones to feed our cells. As red blood cells and other parts of the body are unable to use this alternative ‘fuel’, the liver produces the required glucose from fats and proteins.3 This change of diet can initially cause flu-like symptoms that generally disappear after a few days. Among the unpleasant side effects, constipation and bad breath may last as long as the body is in ketosis. Reintroducing carbohydrates kicks the body out of ketosis, as these remain our bodies’ favourite source of energy.

An upside-down pyramid and the ‘macronutrient war’

LCHF diets replace the carbohydrates on our plates with lipids, thereby turning the food pyramid that has dominated nutritional guidelines in industrialised countries for over 50 years upside down. An LCHF meal generally comprises 70% fats, 25% proteins and 5% carbohydrates. The keto diet bears many similarities to the Atkins diet, popular in the 1970s​.

What if this collective keto craze was not so much about pardoning fats, but rather questioning the way we consume sugar? ‘Eating keto’ also means taking sides in the ‘macronutrient war’4 which pitches ‘anti-fats’ against ‘anti-sugars’. Between beliefs, anecdotes and a plethora of hyperbolic testimonials on social media, it is becoming more and more difficult to tell fact from fiction. For decades, even scientists have had divided opinions. On one hand, we have Dr Ancel Keys and his Seven Countries Study (1958) on the link between high levels of cholesterol, diet and cardiovascular disease. Despite selection biases, his results blame fat consumption.5 On the other, there is Professor John Yudkin, whose book Pure, White and Deadly (1972) points the finger at sugar consumption. However, due to a lack of institutional support, this theory fell by the wayside. The fear of fat reached a peak in the early 1990s, when studies linked dietary fat to an increased risk of certain forms of cancer.6 On the basis of a host of diverse and conclusive research studies in nutrition, and in the absence of differing results, public health organisations spent decades creating and adjusting models of a balanced diet based on carbohydrates, to which the food industry conformed with low-fat products.

In the face of increasing rates of obesity and cardiovascular disease in the late 1990s, doubts began to resurface. Even more alarming, the average BMI7 has been rising since the 1970s.8 Could sugar be the culprit?9 The situation seems far more complex than that because, for an equal energy value, our bodies behave differently depending on the type of carbohydrates10 consumed. More and more nutritionists and doctors are turning towards LCHF diets to treat people suffering from metabolic disorders such as obesity, high cholesterol, glucose intolerance, insulin resistance and type 2 diabetes, generally with satisfactory results.11


Who is right?

Science does not yet know the long-term effects of LCHF diets on the human body. Such diets are also difficult to stick to for any length of time.12 However, the use of keto diets in medicine is nothing new. They are prescribed to treat some serious health problems, with more or less conclusive results, and often when there is a lack of medication or when it no longer works. This has been the case for patients with drug-resistant epilepsy for about a century now.13 Recent research has produced some interesting possibilities in the treatment of Alzheimer’s,14 which some researchers even refer to as ‘type 3 diabetes’.15 It is important to bear in mind that keto is above all a medical diet, not aiming for weight loss, and that is prescribed on the basis of a risk-benefit assessment.16 It is therefore strongly recommended that people seek medical advice before embarking on the keto adventure in the hope of losing a few extra pounds.

1. BENDER, 2014, pp. 5-6

2. The depletion of glycogen (sugar stored in the liver and muscles) is accompanied by rapid initial weight loss, which is mainly water, as water comprises 75% of the total weight of glycogen in our body. In other words, it requires 3 grams of water to store 1 gram of glycogen. See NEWSHOLME LEECH, 2011

3. This is known as gluconeogenesis.BENDER, 2014, p. 160

4. SCRINIS, 2015

5. [accessed on17.01.2019].


7. Body mass index, calculated from a person’s weight and height (weight in kilograms divided by height in metres squared).



10.,,, & [accessed on 20.03.2019]


12. [Accessed on 20.03.2019]




16. If the consumption of certain kinds of fruit, vegetables and cereals is reduced, or even stopped altogether, there may be significant vitamin and mineral deficiencies (vitamin D, calcium, citrates, etc.) and supplements may be necessary in order to prevent conditions such as bone demineralisation and the potential formation of kidney stones, among others. In addition, favouring animal fats can increase the risk of cardiovascular disease.Cf. [accessed on 17.06.2019].

BAILEY, Elizabeth E., PFEIFER, Heidi H. & THIELE, Elizabeth A., 2005. The use of diet in the treatment of epilepsy. Epilepsy & Behavior. 02.2005. Vol. 6, no. 1, pp. 4-8. DOI

BENDER, David A., 2014. Introduction to Nutrition and Metabolism. Boca Raton, London, New York: CRC Press.

BERKEL, Annemiek A. van, IJFF, Dominique M. & VERKUYL, Jan Martin, 2018. Cognitive benefits of the ketogenic diet in patients with epilepsy: A systematic overview. Epilepsy & Behavior. 10.2018. Vol. 87, pp. 69-77. DOI

BROOM, Gina M., SHAW, Ian C. & RUCKLIDGE, Julia J., 2019. The ketogenic diet as a potential treatment and prevention strategy for Alzheimer's disease. Nutrition. 04.2019. Vol. 60, pp. 118-121. DOI

KATAN M.B., GRUNDY S.M. & WILLETT W.C., 1997. Should a low-fat, high-carbohydrate diet be recommended for everyone? Beyond low-fat diets. New England Journal of Medicine. 21.08.1997. Vol. 337, no. 8, pp. 563-567.

KOSINSKI, Christophe & JORNAYVAZ, François R., 2017. Diètes cétogènes, la solution miracle ?. Revue médicale suisse. 2017. Vol. 13, no 565, pp. 1145-1147. Available on: [accessed on 28.02.2019].

LANGE, Klaus W., LANGE, Katharina M., MAKULSKA-GERTRUDA, Ewelina et al., 2017. Ketogenic diets and Alzheimer’s disease. Food Science and Human Wellness. 03.2017. Vol. 6, no. 1, pp. 1-9. DOI

NCD RISK FACTOR COLLABORATION (NCD-RISC), 2017. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2,416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet. 16.12.2017. Vol. 390, no. 10113, pp. 2627-2642. DOI

NEWSHOLME, Eric & LEECH, Tony, 2011. Functional Biochemistry in Health and Disease. Hoboken: Wiley-Blackwell.

PRENTICE R. L. & SHEPPARD L, 1990. Dietary fat and cancer: consistency of the epidemiologic data, and disease prevention that may follow from a practical reduction in fat consumption. Cancer Causes Control. 11.1990. Vol. 1, no. 3, p. 253. Available on: [accessed on 17.01.2019].

SCRINIS, Gyorgy, 2015. Nutritionism: The Science and Politics of Dietary Advice [online]. Columbia University Press Scholarship. [Accessed on 04.03.2019]. Available on:

Jelena Ristic
Curator and Head of Collection
Vevey, Switzerland
After graduating in Humanities and Museology, since 2017, Jelena Ristic has worked as the curator in charge of the Alimentarium collection.

Add new comment

alimentarium magazine
Our monthly newsletter keeps you up-to-date so you can be the first to discover our latest articles and videos. Explore, learn and join in!
subscribe now